Councils and universities in Glasgow, Dundee and Aberdeen are collaborating to deliver Advanced Highers at special hubs.
Universities say the partnerships also demonstrate a commitment to widening access to pupils in disadvantaged communities.
For example, Glasgow Caledonian University welcomes hundreds of pupils from around the city to study every week, with priority given to under-represented groups whose schools might be limited in the subjects they can offer.
At Aberdeen University, pupils studying Advanced Higher sciences attend events where they get to use laboratory equipment with the help of academic staff and student demonstrators. Glasgow University offers similar provision too.
Dundee University enables up to 120 pupils a year to study Advanced Highers. It also offers programmes in art, architecture and design. And the Open University lets S6 pupils study first-year university modules.
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